Fulfilled promise

Vitamin D and cancer: the promise not yet fulfilled.

The negative association of the latitude where people live and the incidence of non cutaneous cancer in that population in North America have been demonstrated in many studies for many types of cancer. Since the intensity of UVB exposure decreases with increasing latitude, and UVB exposure provides the mechanism for vitamin D production in the skin, the hypothesis that increased vitamin D provi...

Gene expression profiling in MS: a fulfilled promise?

Clinical applications of tissue Doppler imaging: a promise fulfilled.

The clinical applications of tissue Doppler imaging in the assessment of left ventricular diastolic function have moved from the experimental lab to clinical practice.

Open Communication and Discussion Facilitate Reconciliation: The Promise Fulfilled

For the benefit of those unfamiliar with the topic, I’d like to summarize the chain of events. The letter that was published accused Israel of terrible atrocities. However, there was no evidence for the accusations, and it came to light following publication that some of the authors were known anti-Semites with connections to a modern-day Nazi supporter. A storm of criticism fell on The Lancet ...

Epidermal growth factor receptor inhibitors for the treatment of colorectal cancer: a promise fulfilled?

The epidermal growth factor receptor (EGFR) is commonly expressed in colorectal cancers but not in most normal tissues, raising the possibility that this receptor could serve as a target for highly selective therapy. Based on preclinical studies demonstrating that antagonists of EGFR resulted in the inhibition of tumor growth, the development of clinical reagents has been aggressively pursued. ...